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Antibodies
Anti-EAAT2 antibody
Anti-EAAT2 antibody from Abcam
Be the first to write a review!
Citations:
(73)
Supplier Page
Supplier Page from
Abcam for
Anti-EAAT2 antibody
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-EAAT2 antibody
Company
Abcam
Price
Pricing Info
Supplier Page
View Supplier Product Page
Catalog Number
ab41621
Antibody Type
Primary
Isotype
IgG
Clonality
Polyclonal
Quantity
100 UG
Host
Rabbit
Applications
Immunocytochemistry/ Immunofluorescence, Western blot
Conjugate/Tag
Unconjugated
Concentration
0.9 mg/ml
Gene Name
SLC1A2
Reactivity
Mouse, Rat
Target
EAAT2
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (73)
(1)
Single-cell analysis reveals region-heterogeneous responses in rhesus monkey spinal cord with complete injury
Nature communications
August 9, 2023
Fan Y, Wu X, Han S, Zhang Q, Sun Z, Chen B, Xue X, Zhang H, Chen Z, Yin M,
et al
.
(
Wako
,
019-19741
,
1:500
), AIF1 (
Abcam
,
ab5076
,
1:500
),
IL-33
(
Abcam
,
ab207737
,
1:200
), SLC1A2 (
Abcam
,
ab41621
,
1:200
), Tuj-1 (
Millipore
,
05-559
,
1:500
),
GPNMB
(
Abcam
,
ab235873
,
1:400
),
VCAN
(
Invitrogen
,
MA5-34654
,
(2)
Aberrant adenosine signaling in patients with focal cortical dysplasia
Molecular Neurobiology
August 1, 2023
Mengyi Guo, Jing Zhang, Jing Wang, Xiongfei Wang, Qing Gao, Chongyang Tang, Jiahui Deng, Zhonghua Xiong, Xiangru Kong, Yuguang Guan,
et al.
ab79714
,
1:100
,
Abcam
),
mTOR
(monoclonal
mouse
,
SAB2702296
,
1:50
,
Sigma
), GLT-1 (polyclonal rabbit,
ab41621
,
1:100
,
Abcam
), GFAP (monoclonal
mouse
, DAKO; Glostrup, Denmark,
1:4000
), Iba-1 (monoclonal
mouse
,
ab15690
,
(3)
Chronic exposure to inorganic arsenic and fluoride induces redox imbalance, inhibits the transsulfuration pathway, and alters glutamate receptor expression in the brain, resulting in memory impairment in adult male mouse offspring
Archives of Toxicology
July 23, 2023
Wendy L. González-Alfonso, Petrosyan Pavel, Hernández-Mercado Karina, Luz M. Del Razo, Luz C. Sanchez-Peña, Angélica Zepeda, María E. Gonsebatt
Western blots
, primary rabbit antibodies against xCT (
ab37185
),
EAAT3
(
ab124802
), GLAST (
ab416
), GLT1 (
ab41621
), NR2B (
ab65783
),
GluA2
(
ab133477
), Synaptophysin (SY38,
ab8049
),
CBS
(
ab135626
), and
CSE
(
ab151769
)
(4)
Glutamate-releasing BEST1 channel is a new target for neuroprotection against ischemic stroke with wide time window
Acta Pharmaceutica Sinica B
July 1, 2023
Shuai Xiong, Hui Xiao, Meng Sun, Yunjie Liu, Ling Gao, Ke Xu, Haiying Liang, Nan Jiang, Yuhui Lin, Lei Chang,
et al.
anti-β-actin (
1:2000
;
Bioss
, Cat#
bs-0061R
, RRID: AB_10855480), rabbit anti-GLT-1 (
1:1000
,
Abcam
, Cat#
ab41621
, RRID: AB_941782); rabbit anti-GluN2B (
1:4000
,
Cell Signaling Technology
, Cat#
4207
, RRID: AB_1264223);
(5)
Conditional deletion of LRRC8A in the brain reduces stroke damage independently of swelling-activated glutamate release
iScience
May 19, 2023
Mustafa Balkaya, Preeti Dohare, Sophie Chen, Alexandra L. Schober, Antonio M. Fidaleo, Julia W. Nalwalk, Rajan Sah, Alexander A. Mongin
HRP-conjugated",
Millipore-Sigma
,cat. #
A3854
; RRID:AB_262011 Rabbit polyclonal anti-GLT1 (EAAT2),
Abcam
,cat. #
ab41621
; RRID:AB_941782
Mouse
monoclonal anti-glial fibrillary acidic protein (GFAP),
Millipore-Sigma
,cat. #
MAB360
;
(6)
N-Acetylcysteine normalizes brain oxidative stress and neuroinflammation observed after protracted ethanol abstinence: a preclinical study in long-term ethanol-experienced male rats
Psychopharmacology (Berl)
April 1, 2023
Sandra Fernández-Rodríguez, María José Cano-Cebrián, Claudia Esposito-Zapero, Salvador Pérez, Consuelo Guerri, Teodoro Zornoza, Ana Polache
solution and incubated overnight at 4 °C: anti-
GAPDH
(
1:2000
#
G9545
Sigma-Aldrich
), anti-GLT-1 (
1:5000
ab41621
from
Abcam
),
anti-xCT
(
1:1000
ab175186
from
Abcam
), and anti-GLAST (
1:2000
NB100-1869 from NovusBio).
(7)
Dysregulation of AMPA Receptor Trafficking and Intracellular Vesicular Sorting in the Prefrontal Cortex of Dopamine Transporter Knock-Out Rats
Biomolecules
March 11, 2023
Giorgia Targa, Francesca Mottarlini, Beatrice Rizzi, Damiana Leo, Lucia Caffino, Fabio Fumagalli
Cell Signaling Technology
, Danvers, MA, USA, cod.
12331
, RRID: AB_2797887), anti-GLT-1 (
1:2000
,
Abcam
, Boston, MA, USA, cod.
Ab41621
, RRID: AB_941782), anti-GluA1 (
1:1000
,
Cell Signaling Technology
, cod.
13185
, RRID: AB_2732897), anti-GluA2
(8)
Young Astrocytic Mitochondria Attenuate the Elevated Level of CCL11 in the Aged Mice, Contributing to Cognitive Function Improvement
International Journal of Molecular Sciences
March 8, 2023
Ryosuke Tashiro, Dan Ozaki, Jesus Bautista-Garrido, Guanghua Sun, Lidiya Obertas, Alexis S. Mobley, Gab Seok Kim, Jaroslaw Aronowski, Joo Eun Jung
followed by
incubation
with primary antibodies against excitatory amino acid transporter 2 (EAAT-2) (
ab41621
,
Abcam
), vimentin (
ab92547
, Abcam), and aldehyde dehydrogenase 1 family member L1 (ALDH1L1) (
ab87117
,
(9)
Pinostrobin alleviates chronic restraint stress‑induced cognitive impairment by modulating oxidative stress and the function of astrocytes in the hippocampus of rats
Biomedical Reports
February 2, 2023
Sitthisak Thongrong, Serm Surapinit, Tichanon Promsrisuk, Jinatta Jittiwat, Ratchaniporn Kongsui
MAB5628
,
MilliporeSigma
), or rabbit anti-excitatory amino acid transporter 2 (EAAT2; (
1:200
, cat. no.
ab41621
,
Abcam
) at 4˚C overnight. The sections were washed in 0.1 M PBS for 30 min and incubated for 2 h at
(10)
Primary glia cells from bank vole propagate multiple rodent-adapted scrapie prions
Scientific Reports
December 1, 2022
Karla A. Schwenke, Joo-Hee Wälzlein, Agnieszka Bauer, Achim Thomzig, Michael Beekes
recombinant anti-GFAP PE-conjugated [REA335, Miltenyi Biotec, Germany]:
1:100
; polyclonal rabbit anti-GLT-1 [
ab41621
,
Abcam
, UK]:
1:200
; monoclonal
mouse
anti-PrP [SAF84, Bertin, France]:
1:400
) and subsequently, after
(11)
Inhibition of Synaptic Glutamate Exocytosis and Prevention of Glutamate Neurotoxicity by Eupatilin from Artemisia argyi in the Rat Cortex
International journal of molecular sciences
November 2, 2022
Lu CW, Wu CC, Chiu KM, Lee MY, Lin TY, Wang SJ.
(#3700) were acquired from
Cell Signaling
(Beverly, MA, USA). Antibodies against EAAT1 (
ab416
) and EAAT2 (
ab41621
) were acquired from
Abcam
(Cambridge, UK). Horseradish peroxidase-conjugated secondary antibodies (
GTX213110-01
;
(12)
Electroacupuncture relieves hyperalgesia by regulating neuronal–glial interaction and glutamate transporters of spinal dorsal horns in rats with acute incisional neck pain
Frontiers in Neuroscience
October 26, 2022
Jun-ying Wang, Jin-ling Zhang, Shu-ping Chen, Yong-hui Gao, Jian-liang Zhang, Yu Chen, Yue Zhang, Pei-jing Rong, Jun-ling Liu
mouse anti-GFAP and rabbit anti-GLAST (
1:200
,
ab416
,
Abcam
, Waltham, MA, USA)/rabbit anti-GLT-1 (
1:200
,
ab41621
,
Abcam
, Waltham, MA, USA) overnight at 4°C. Next, the sections were incubated with fluorescent secondary
(13)
Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer''s disease
Cell reports
August 23, 2022
Shah D, Gsell W, Wahis J, Luckett ES, Jamoulle T, Vermaercke B, Preman P, Moechars D, Hendrickx V, Jaspers T,
et al
.
600-401-379
,
1:500
), rabbit anti-
IP3R2
(
Thermofischer
, ID
PA1904
,
1:200
), rabbit-anti-GLT1 (
Abcam
, ID
ab41621
,
1:500
). Secondary antibodies included:
goat
anti-
guinea pig
(Alexa 594,
Jackson
Immunolabs, ID
106-585-003
,
(14)
Cellular and Molecular Gradients in the Ventral Horns With Increasing Distance From the Injury Site After Spinal Cord Contusion
Frontiers in Cellular Neuroscience
February 10, 2022
Ilyas M. Kabdesh, Yana O. Mukhamedshina, Svetlana S. Arkhipova, Davran K. Sabirov, Maxim S. Kuznecov, Alexandra B. Vyshtakalyuk, Albert A. Rizvanov, Victoria James, Yuri A. Chelyshev
Antibody,Host,Dilution,Source
GFAP
,
mouse
,"
1:1,000
(WB)",
Santa Cruz
(
sc-33673
) GLT-1,rabbit,"
1:1,000
(WB)",
Abcam
(
ab41621
) β-III-tubulin,
mouse
,
1:500
(WB),
Santa Cruz
(
sc-5274
)
NG2
,
mouse
,
1:100
(
IHC
)
1:100
(IEM),
Sigma–Aldrich
(15)
Manganese phosphorylates Yin Yang 1 at serine residues to repress EAAT2 in human H4 astrocytes
Toxicology Letters
February 1, 2022
Asha Rizor, Edward Pajarillo, Deok-Soo Son, Michael Aschner, Eunsook Lee
dimethyl sulfoxide (DMSO
) were purchased from
MilliporeSigma
(St. Louis, MO). Antibodies for EAAT2 (
ab41621
), phosphoserine (
ab9332
) and goat anti-rabbit IgG (
ab97051
) were obtained from
Abcam
(Cambridge, MA).
(16)
Alpha-Asaronol Alleviates Dysmyelination by Enhancing Glutamate Transport Through the Activation of PPARγ-GLT-1 Signaling in Hypoxia-Ischemia Neonatal Rats
Frontiers in pharmacology
January 1, 2022
Ge Y, Zhen F, Liu Z, Feng Z, Wang G, Zhang C, Wang X, Sun Y, Zheng X, Bai Y,
et al
.
(GFAP,
Proteintech
,
16825-1-AP
,
1:400
),
mouse
GLT-1
(
Santa Cruz
,
sc-365634
,
1:200
), rabbit
GLT-1
(
Abcam
,
ab41621
,
1:400
),
mouse
GLT-1
(Santa Cruz,
sc-365634
,
1:100
),
mouse
myelin basic protein (MBP,
Santa Cruz
,
sc-271524
,
(17)
Late adolescence mortality in mice with brain-specific deletion of the volume-regulated anion channel subunit LRRC8A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
October 1, 2021
Wilson CS, Dohare P, Orbeta S, Nalwalk JW, Huang Y, Ferland RJ, Sah R, Scimemi A, Mongin AA.
anti-GAT-1
(
Abcam
, cat. #
ab72448
, RRID:AB_1268935,
1:500
), rabbit polyclonal anti-GLT-1 (
Abcam
, cat. #
ab41621
, RRID:AB_941782,
1:10,000
), or rabbit polyclonal anti-glutamine synthetase (
Millipore-Sigma
, cat. #
G2781
,
(18)
Xueshuantong Improves Functions of Lymphatic Ducts and Modulates Inflammatory Responses in Alzheimer’s Disease Mice
Frontiers in Pharmacology
September 28, 2021
Rui Zheng, Yang-mei Huang, Qiang Zhou
primary antibody (anti-AQP4,
1:1000
, Cat. No.
ab46182
,
Abcam
, United Kingdom; anti-GLT1,
1:1000
, Cat. No.
ab41621
,
Abcam
, United Kingdom; anti-MMP-9,
1:500
, Cat. No.
ab38898
,
Abcam
, United Kingdom; anti-GAPDH,
1:10000
,
(19)
Manganese-induced reactive oxygen species activate IκB kinase to upregulate YY1 and impair glutamate transporter EAAT2 function in human astrocytes in vitro
NeuroToxicology
September 1, 2021
Asha Rizor, Edward Pajarillo, Ivan Nyarko-Danquah, Alexis Digman, Leyah Mooneyham, Deok-Soo Son, Michael Aschner, Eunsook Lee
diacetate (CM-H2DCFDA) was purchased from Life Technologies, Inc. (Carlsbad, CA). Antibodies for EAAT2 (
ab41621
), IKK-β (
ab32135
) and phospho-IKK-β (
ab59195
) were obtained from
Abcam
(Cambridge, MA); antibodies for
(20)
Combining multiomics and drug perturbation profiles to identify muscle-specific treatments for spinal muscular atrophy
JCI Insight
July 8, 2021
Katharina E. Meijboom et al.
membrane
was then probed overnight at 4°C with primary antibodies (rabbit anti–GLT-1,
1:1000
,
Abcam
,
ab41621
;
mouse
anti-vinculin,
1:200,000
,
Sigma-Aldrich
,
V9131
) in Odyssey Blocking Buffer and 0.1%
Tween-20
.
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Anti-EAAT2 antibody from Abcam
Supplier Page
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Product Specs
Company Info
Citations
Reviews
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